Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[6-(difluoromethyl)-5-[4-oxo-7-[4-(trifluoromethyl)phenyl]-3H-quinazolin-2-yl]pyridin-3-yl]methyl]-2-methylpropanamide
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 PubChem ID
CID: 137169028
Canonical SMILES
CC(C)C(=O)NCc1cnc(C(F)F)c(c1)-c1nc2cc(ccc2c(=O)[nH]1)-c1ccc(cc1)C(F)(F)F
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Compound Formula C26H21F5N4O2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS