Brief Information of the Compound and Protein
Compound Name
(S)-N-((S)-3-cyclohexyl-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide
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PubChem ID
CID: 101874274
Canonical SMILES
COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC2CCCCC2)C(=O)[C@@]2(C)CO2)cc1
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Compound Formula C31H46N4O7
Compound Structure
Protein Name
Proteasome subunit beta type-8
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28062
Gene Name
PSMB8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000174 Raji Homo sapiens (Human)  1
1
IC50 = 6.6 nM
   TI
   LI
   LO
   TS
CL000186 RPMI-8226 Homo sapiens (Human)  1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS