Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
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 PubChem ID
CID: 23642227
SID: 46502227
Canonical SMILES
COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1
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Compound Formula C31H40N4O7
Compound Structure
Protein Name
 Protein Info 
Proteasome subunit beta type-8
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28062
Gene Name
PSMB8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 39 nM
   TI
   LI
   LO
   TS
CL000174 Raji
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.7 nM
   TI
   LI
   LO
   TS
CL000186 RPMI-8226
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30.5 nM
2 IC50 = 37.9 nM
3 IC50 = 39 nM
4 IC50 = 52 nM
5 IC50 = 450 nM