Brief Information of the Compound and Protein
Compound Name
(7R)-N-hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide
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PubChem ID
CID: 92045024
Canonical SMILES
ONC(=O)c1ccc2CC[C@H](Cc2c1)Nc1nccc(n1)-c1cccnc1
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Compound Formula C20H19N5O2
Compound Structure
Protein Name
Histone deacetylase 6
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIb
Uniprot ID
Q9UBN7
Gene Name
HDAC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
EC50 = 1600 nM
   TI
   LI
   LO
   TS
2
EC50 = 1640 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 48 nM
2 IC50 = 50 nM