Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[1-(2,2-difluoro-4-hydroxybutyl)-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
    Show/Hide
 PubChem ID
CID: 59281343
Canonical SMILES
Cc1nn(CC(F)(F)CCO)c(c1-c1ccc2OCC(=O)Nc2c1)-c1ccc(F)cc1
    Show/Hide
Compound Formula C22H20F3N3O3
Compound Structure
Protein Name
 Protein Info 
Mineralocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 2
Uniprot ID
P08235
Gene Name
NR3C2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 540 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS