Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-[[2-(4-chlorophenyl)-6-[2-(dimethylamino)-2-oxoethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
    Show/Hide
 PubChem ID
CID: 118705739
Canonical SMILES
CN(C)C(=O)COc1cccc(c1CN1CCN(CC1)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(N[C@H](CCN2CCOCC2)CSc2ccccc2)c(c1)S(=O)(=O)C(F)(F)F)-c1ccc(Cl)cc1
    Show/Hide
Compound Formula C49H54ClF3N6O8S3
Compound Structure
Protein Name
 Protein Info 
Apoptosis regulator Bcl-2
Protein Classification
Ion channel
>
Other ion channel
>
Miscellaneous ion channel
>
Bcl-2 family
Uniprot ID
P10415
Gene Name
BCL2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000121 FDC-P1
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 10 nM