Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide
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 PubChem ID
CID: 24978538
SID: 57304426
Canonical SMILES
CC1(C)CCC(=C(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCOCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1
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Compound Formula C47H55ClF3N5O6S3
Compound Structure
Protein Name
 Protein Info 
Apoptosis regulator Bcl-2
Protein Classification
Ion channel
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Other ion channel
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Miscellaneous ion channel
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Bcl-2 family
Uniprot ID
P10415
Gene Name
BCL2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000121 FDC-P1
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 < 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10.3 nM
2 Ki < 0.01 nM
3 Ki = 0.044 nM
4 Ki < 0.1 nM
5 Ki < 0.5 nM
6 Ki < 1 nM