Brief Information of the Compound and Protein
Compound Name
1-[(E)-6-(3,4-dihydro-1H-isoquinolin-2-yl)hex-3-enyl]-3H-indol-2-one
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PubChem ID
CID: 102364516
Canonical SMILES
O=C1Cc2ccccc2N1CC\C=C\CCN1CCc2ccccc2C1
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Compound Formula C23H26N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 7
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P34969
Gene Name
HTR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 230 nM
   TI
   LI
   LO
   TS
2
IC50 = 2200 nM
   TI
   LI
   LO
   TS
3
Ki = 0.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.7 nM