Brief Information of the Compound and Protein
Compound Name
5-[3-(imidazo[1,2-a]pyridin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyridine-2-carbonitrile
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PubChem ID
CID: 54759721
SID: 131523884
Canonical SMILES
N#Cc1ccc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1
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Compound Formula C18H11N9
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17 nM