Brief Information of the Compound and Protein
Compound Name
6-[[5-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyrazin-3-yl]methyl]quinoline
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PubChem ID
CID: 86566650
Canonical SMILES
Cn1cc(cn1)-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1
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Compound Formula C19H15N7
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 9.9 nM
2 IC50 = 96 nM