Brief Information of the Compound and Protein
Compound Name
5-[[5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazin-3-yl]methyl]-1H-thieno[3,2-c]pyrazole
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PubChem ID
CID: 68355550
Canonical SMILES
Cn1cc(cn1)-c1cnc2nnn(Cc3cc4[nH]ncc4s3)c2n1
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Compound Formula C14H11N9S
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM