Brief Information of the Compound and Protein
Compound Name
2-[4-[3-[(1R)-1-pyrazolo[1,5-a]pyridin-5-ylethyl]triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
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PubChem ID
CID: 68289397
Canonical SMILES
C[C@H](c1ccn2nccc2c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
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Compound Formula C18H17N9O
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM