Brief Information of the Compound and Protein
Compound Name
5-(1-methylpyrazol-4-yl)-3-([1,2,4]triazolo[1,5-a]pyridin-6-ylmethyl)triazolo[4,5-b]pyrazine
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PubChem ID
CID: 53261806
SID: 124403144
Canonical SMILES
Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncnn4c3)c2n1
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Compound Formula C15H12N10
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 26 nM