Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
    Show/Hide
 PubChem ID
CID: 10236758
SID: 15238656
Canonical SMILES
CCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1
    Show/Hide
Compound Formula C21H32N2O
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  9
1
EC50 = 34.67 nM
   TI
   LI
   LO
   TS
2
EC50 = 60.26 nM
   TI
   LI
   LO
   TS
3
EC50 = 102.33 nM
   TI
   LI
   LO
   TS
4
EC50 = 120.23 nM
   TI
   LI
   LO
   TS
5
EC50 = 190.55 nM
   TI
   LI
   LO
   TS
6
EC50 = 263.03 nM
   TI
   LI
   LO
   TS
7
EC50 = 831.76 nM
   TI
   LI
   LO
   TS
8
IC50 = 173.78 nM
   TI
   LI
   LO
   TS
9
IC50 = 1584.89 nM
   TI
   LI
   LO
   TS