Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-[4-[5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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 PubChem ID
CID: 118719921
Canonical SMILES
CN1CCC=C(C1)c1nsnc1OCCCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1
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Compound Formula C30H43N5O2S
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 6.761 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 20.42 nM
   TI
   LI
   LO
   TS
2
IC50 = 645.65 nM
   TI
   LI
   LO
   TS
3
IC50 = 4265.8 nM
   TI
   LI
   LO
   TS
4
IC50 = 5370.32 nM
   TI
   LI
   LO
   TS