Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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 PubChem ID
CID: 118719926
Canonical SMILES
OCCCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1
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Compound Formula C22H34N2O2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 467.74 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 112.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 204.17 nM
   TI
   LI
   LO
   TS
3
IC50 = 28.84 nM
   TI
   LI
   LO
   TS
4
IC50 = 10000 nM
   TI
   LI
   LO
   TS
5
IC50 = 26302.68 nM
   TI
   LI
   LO
   TS