Brief Information of the Compound and Protein
Compound Name
N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-4-methoxy-2-[4-[(2S)-piperidine-2-carbonyl]piperazin-1-yl]phenyl]prop-2-enamide
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PubChem ID
CID: 118719575
Canonical SMILES
COc1cc(N2CCN(CC2)C(=O)[C@@H]2CCCCN2)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12
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Compound Formula C31H34ClN9O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
IC50 = 31000 nM
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