Brief Information of the Compound and Protein
Compound Name
4-[[2-[(2R)-2-methyl-4-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]piperazin-1-yl]pyrimidin-5-yl]oxymethyl]pyridine-3-carbonitrile
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PubChem ID
CID: 90665949
Canonical SMILES
C[C@@H]1CN(CCN1c1ncc(OCc2ccncc2C#N)cn1)c1nnc(o1)C(F)(F)F
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Compound Formula C19H17F3N8O2
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q8TDV5
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 25.12 nM
   TI
   LI
   LO
   TS
CL000107 HEK293S Homo sapiens (Human)  1
1
EC50 = 28 nM
   TI
   LI
   LO
   TS