Brief Information of the Compound and Protein
Compound Name
methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-hydroxybenzoate
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PubChem ID
CID: 16124726
Canonical SMILES
COC(=O)c1ccc(O)c(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1
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Compound Formula C26H29NO5
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  2
1
IC50 = 2440 nM
   TI
   LI
   LO
   TS
2
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 21000 nM
   TI
   LI
   LO
   TS