Brief Information of the Compound and Protein
Compound Name
3-[8-(3,4-dimethoxyanilino)imidazo[1,2-a]pyrazin-6-yl]-N,N-dimethylbenzamide
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PubChem ID
CID: 44188382
SID: 85184022
Canonical SMILES
COc1ccc(Nc2nc(cn3ccnc23)-c2cccc(c2)C(=O)N(C)C)cc1OC
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Compound Formula C23H23N5O3
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 615 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 112 nM