Brief Information of the Compound and Protein
Compound Name
6-(1H-indazol-6-yl)-N-(3-methoxyphenyl)imidazo[1,2-a]pyrazin-8-amine
    Show/Hide
PubChem ID
CID: 59473155
Canonical SMILES
COc1cccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)c1
    Show/Hide
Compound Formula C20H16N6O
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 374 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.5 nM