Brief Information of the Compound and Protein
Compound Name
3-[8-(3,4-dimethoxyanilino)imidazo[1,2-a]pyrazin-6-yl]-N-methylbenzamide
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PubChem ID
CID: 44188551
SID: 85184195
Canonical SMILES
CNC(=O)c1cccc(c1)-c1cn2ccnc2c(Nc2ccc(OC)c(OC)c2)n1
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Compound Formula C22H21N5O3
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 619 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 50.2 nM