Brief Information of the Compound and Protein
Compound Name
N-(4-carbamoylphenyl)-3-[8-(3,4-dimethoxyanilino)imidazo[1,2-a]pyrazin-6-yl]benzamide
    Show/Hide
PubChem ID
CID: 44187112
SID: 85182777
Canonical SMILES
COc1ccc(Nc2nc(cn3ccnc23)-c2cccc(c2)C(=O)Nc2ccc(cc2)C(N)=O)cc1OC
    Show/Hide
Compound Formula C28H24N6O4
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 105 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.3 nM