Brief Information of the Compound and Protein
Compound Name
ethyl (2R)-2-methyl-3-phenyl-2-[3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]propanoate
    Show/Hide
PubChem ID
CID: 66964295
Canonical SMILES
CCOC(=O)[C@](C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F
    Show/Hide
Compound Formula C25H22F3N3O2
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q7TQP3
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 19 nM
   TI
   LI
   LO
   TS
CL000657 GLUTag Mus musculus (Mouse)  1
1
EC50 = 330 nM
   TI
   LI
   LO
   TS