Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(3aR,5S,6aR)-5-[(3-methoxyoxan-4-yl)amino]-2,3,4,5,6,6a-hexahydrocyclopenta[b]thiophen-3a-yl]-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone
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 PubChem ID
CID: 71768830
Canonical SMILES
COC1COCCC1N[C@@H]1C[C@H]2SCC[C@]2(C1)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F
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Compound Formula C23H30F3N3O3S
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
IC50 = 109 nM
   TI
   LI
   LO
   TS