Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BUPRENORPHINE
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 PubChem ID
CID: 9848990
SID: 14882841
Canonical SMILES
CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45
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Compound Formula C29H41NO4
Compound Structure
Protein Name
 Protein Info 
Nociceptin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 116 nM
   TI
   LI
   LO
   TS
2
Ki = 77 nM
   TI
   LI
   LO
   TS
3
Ki = 77.4 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 1480 nM
   TI
   LI
   LO
   TS
2
Ki = 212 nM
   TI
   LI
   LO
   TS