Brief Information of the Compound and Protein
Compound Name
(3S)-3-cyclopropyl-3-[2-[[4-(5-fluoro-2-methoxypyridin-4-yl)-3-[(1R)-1-methoxy-2,2-dimethylpropyl]phenyl]methoxy]pyridin-4-yl]propanoic acid
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PubChem ID
CID: 86288852
Canonical SMILES
CO[C@@H](c1cc(COc2cc(ccn2)[C@@H](CC(O)=O)C2CC2)ccc1-c1cc(OC)ncc1F)C(C)(C)C
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Compound Formula C30H35FN2O5
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  1
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 162 nM
   TI
   LI
   LO
   TS