Brief Information of the Compound and Protein
Compound Name
(1'R,5R)-3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]spiro[6,7-dihydrocyclopenta[c]pyridine-5,2'-cyclopropane]-1'-carboxylic acid
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PubChem ID
CID: 90655863
Canonical SMILES
COc1cc(c(F)cn1)-c1ccc(COc2cc3c(CC[C@]33C[C@H]3C(O)=O)cn2)cc1[C@@H]1CCCC1(C)C
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Compound Formula C31H33FN2O4
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  1
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 249 nM
   TI
   LI
   LO
   TS