Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,4,6-trimethyl-N-[1,1,1-trifluoro-3-[1-(4-fluorophenyl)indazol-4-yl]oxypropan-2-yl]benzenesulfonamide
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 PubChem ID
CID: 57690902
Canonical SMILES
Cc1cc(C)c(c(C)c1)S(=O)(=O)NC(COc1cccc2n(ncc12)-c1ccc(F)cc1)C(F)(F)F
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Compound Formula C25H23F4N3O3S
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000464 ChaGo-K-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.8 nM
2 IC50 = 36 nM