Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,11R,15R,16R,17S,19S)-22-benzyl-6-hydroxy-12-methyl-2,4,18-trioxa-12,22-diazaheptacyclo[15.4.2.15,9.01,16.011,19.015,19.015,24]tetracosa-5,7,9(24)-trien-23-one
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 PubChem ID
CID: 56589680
SID: 134216819
Canonical SMILES
CN1CC[C@]23[C@@H]4[C@@H]5O[C@@]22CC[C@@]4(OCOc4c(O)ccc(C[C@@H]12)c34)N(Cc1ccccc1)C5=O
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Compound Formula C27H28N2O5
Compound Structure
Protein Name
 Protein Info 
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 478 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 307 nM
   TI
   LI
   LO
   TS