Brief Information of the Compound and Protein
Compound Name
5-[6-(1,4-diazepan-1-yl)pyrazin-2-yl]-3-methyl-2H-indazole
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PubChem ID
CID: 77461137
Canonical SMILES
Cc1n[nH]c2ccc(cc12)-c1cncc(n1)N1CCCNCC1
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Compound Formula C17H20N6
Compound Structure
Protein Name
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
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AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000333 GTM-3 Homo sapiens (Human)  1
1
EC50 = 380 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 36 nM