Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(dimethylamino)-3-[4-(6-pyridin-4-yl-3-pyrrolidin-1-ylpyrazin-2-yl)piperazin-1-yl]propan-2-ol
    Show/Hide
 PubChem ID
CID: 90654805
Canonical SMILES
CN(C)CC(O)CN1CCN(CC1)c1nc(cnc1N1CCCC1)-c1ccncc1
    Show/Hide
Compound Formula C22H33N7O
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000333 GTM-3
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 76 nM