Brief Information of the Compound and Protein
Compound Name
2-(4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-yl)piperazin-1-yl)ethanol
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PubChem ID
CID: 46216813
SID: 96071205
Canonical SMILES
OCCN1CCN(CC1)c1nc(cnc1N1CCCC1)-c1ccncc1
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Compound Formula C19H26N6O
Compound Structure
Protein Name
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000333 GTM-3 Homo sapiens (Human)  1
1
EC50 = 680 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 39 nM
2 IC50 = 78 nM