Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-Methoxyphenyl)-N,5-dimethyl-N-(6-(trifluoromethyl)pyridin-3-yl)isoxazole-4-carboxamide
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 PubChem ID
CID: 76318386
Canonical SMILES
COc1cccc(-c2noc(C)c2C(=O)N(C)c2ccc(C(F)(F)F)nc2)c1
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Compound Formula C19H16F3N3O3
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 618 nM
   TI
   LI
   LO
   TS