Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(4-(4-(N-pyridin-2-ylsulfamoyl)phenylamino)quinazolin-6-yl)acrylamide
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 PubChem ID
CID: 76332992
Canonical SMILES
C=CC(=O)Nc1ccc2ncnc(Nc3ccc(S(=O)(=O)Nc4ccccn4)cc3)c2c1
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Compound Formula C22H18N6O3S
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4390 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9800 nM