Brief Information of the Compound and Protein
Compound Name
4-[3'-(1''H-Imidazol-1''-yl)phenyl]-8-(3'''-iodophenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one
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PubChem ID
CID: 76318478
Canonical SMILES
O=C1CC(c2cccc(-n3ccnc3)c2)=Nc2ccc(-c3cccc(I)c3)cc2N1
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Compound Formula C24H17IN4O
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 = 132 nM
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