Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4aR,10R,10aR)-8-(2-fluoropyridin-3-yl)-10a-methylspiro[1,3,4,4a-tetrahydropyrano[4,3-b]chromene-10,4'-5H-1,3-oxazole]-2'-amine
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 PubChem ID
CID: 67970675
Canonical SMILES
C[C@@]12COCC[C@H]1Oc1ccc(cc1[C@@]21COC(N)=N1)-c1cccnc1F
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Compound Formula C20H20FN3O3
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS