Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[1-[(4-hydroxy-3-propan-2-ylphenyl)methyl]-2-methylindol-4-yl]amino]-2-oxoacetic acid
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 PubChem ID
CID: 24830528
SID: 49852273
Canonical SMILES
CC(C)c1cc(Cn2c(C)cc3c(NC(=O)C(O)=O)cccc23)ccc1O
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Compound Formula C21H22N2O4
Compound Structure
Protein Name
 Protein Info 
Thyroid hormone receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group A
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Nuclear hormone receptor subfamily 1 group A member 2
Uniprot ID
P10828
Gene Name
THRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 590 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM