Brief Information of the Compound and Protein
Compound Name
4-[1-[(4-hydroxy-3-propan-2-ylphenyl)methyl]-2-methylindol-3-yl]butanoic acid
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PubChem ID
CID: 73055021
Canonical SMILES
CC(C)c1cc(Cn2c(C)c(CCCC(O)=O)c3ccccc23)ccc1O
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Compound Formula C23H27NO3
Compound Structure
Protein Name
Thyroid hormone receptor alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group A
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Nuclear hormone receptor subfamily 1 group A member 1
Uniprot ID
P10827
Gene Name
THRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 180 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3400 nM