Brief Information of the Compound and Protein
Compound Name
(4-methylpiperazin-1-yl)-[6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]methanone
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PubChem ID
CID: 25118123
SID: 56442316
Canonical SMILES
CN1CCN(CC1)C(=O)C1CC11CCN(CC1)C1CCOCC1
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Compound Formula C18H31N3O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
2
Ki = 1300 nM
   TI
   LI
   LO
   TS