Brief Information of the Compound and Protein
Compound Name
(4-cyclohexylpiperazin-1-yl)-(6-propan-2-yl-6-azaspiro[2.5]octan-2-yl)methanone
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PubChem ID
CID: 25118479
SID: 56442684
Canonical SMILES
CC(C)N1CCC2(CC2C(=O)N2CCN(CC2)C2CCCCC2)CC1
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Compound Formula C21H37N3O
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
2
Ki = 47 nM
   TI
   LI
   LO
   TS