Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-ethylphenyl)urea
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 PubChem ID
CID: 76321214
Canonical SMILES
CCc1cccc(NC(=O)Nc2ccc(cc2)-c2coc3ncnc(N)c23)c1
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Compound Formula C21H19N5O2
Compound Structure
Protein Name
 Protein Info 
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 25 nM
   TI
   LI
   LO
   TS
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS