Brief Information of the Compound and Protein
Compound Name
1-cyclopentyl-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea
    Show/Hide
PubChem ID
CID: 76321211
Canonical SMILES
O=C(NC1CCCC1)Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1ccccc1
    Show/Hide
Compound Formula C25H24N4O
Compound Structure
Protein Name
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
2
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 7900 nM
   TI
   LI
   LO
   TS