Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-[5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]urea
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 PubChem ID
CID: 76328384
Canonical SMILES
Fc1ccc(cc1NC(=O)Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1cn[nH]c1)C(F)(F)F
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Compound Formula C24H16F4N6O
Compound Structure
Protein Name
 Protein Info 
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
2
IC50 = 16 nM
   TI
   LI
   LO
   TS
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 63 nM
   TI
   LI
   LO
   TS