Brief Information of the Compound and Protein
Compound Name
4-[[2-(3,4-dimethoxyphenyl)quinazolin-4-yl]amino]phenol
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PubChem ID
CID: 72735408
Canonical SMILES
COc1ccc(cc1OC)-c1nc(Nc2ccc(O)cc2)c2ccccc2n1
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Compound Formula C22H19N3O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
2
IC50 = 680 nM
   TI
   LI
   LO
   TS