Brief Information of the Compound and Protein
Compound Name
6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine
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PubChem ID
CID: 5328202
SID: 16366349
Canonical SMILES
COc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cc1OC
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Compound Formula C17H14F3N3O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 1980 nM
   TI
   LI
   LO
   TS
2
IC50 = 2400 nM
   TI
   LI
   LO
   TS