Brief Information of the Compound and Protein
Compound Name
6,7-dimethoxy-N-(4-nitrophenyl)quinazolin-4-amine
    Show/Hide
PubChem ID
CID: 11210677
SID: 16512529
Canonical SMILES
COc1cc2ncnc(Nc3ccc(cc3)[N+]([O-])=O)c2cc1OC
    Show/Hide
Compound Formula C16H14N4O4
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 2460 nM
   TI
   LI
   LO
   TS
2
IC50 = 2920 nM
   TI
   LI
   LO
   TS