Brief Information of the Compound and Protein
Compound Name
4-Anilino quinazoline deriv. 17
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PubChem ID
CID: 651672
SID: 14948672
Canonical SMILES
FC(F)(F)c1cccc(Nc2ncnc3ccccc23)c1
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Compound Formula C15H10F3N3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 940 nM
   TI
   LI
   LO
   TS
2
IC50 = 1550 nM
   TI
   LI
   LO
   TS