Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (3aR,7aS)-7-hydroxy-7-[2-(3-methylphenyl)ethynyl]-3,3a,4,5,6,7a-hexahydro-1H-isoindole-2-carboxylate
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 PubChem ID
CID: 76324428
Canonical SMILES
COC(=O)N1C[C@@H]2CCCC(O)(C#Cc3cccc(C)c3)[C@@H]2C1
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Compound Formula C19H23NO3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1010 nM
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