Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 3-hydroxy-3-[2-(3-methylphenyl)ethynyl]-1-oxa-8-azaspiro[4.5]decane-8-carboxylate
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 PubChem ID
CID: 72546752
Canonical SMILES
COC(=O)N1CCC2(CC(O)(CO2)C#Cc2cccc(C)c2)CC1
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Compound Formula C19H23NO4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 813 nM
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